Better diagnosis to improve breast cancer treatment

Breast cancer patients will soon have a better chance of fighting the disease thanks to new pathology guidelines created by University of Queensland researchers.

The guidelines allow pathologists to identify which patients have more aggressive forms of breast cancer, which means they can be classified appropriately and their treatment can be tailored.

Physical activity

Exercise is one of the best things women can do for themselves, says director of the Program for Young Women with Breast Cancer at Dana-Farber Cancer Institute. It doesn’t mean marathons or hot yoga, but walking three to five times a week can make a huge difference in terms of energy, stamina and how you feel during treatment. Partridge says that while exercising during treatment won’t be easy for every woman with breast cancer, it can be worthwhile if there are days during treatment cycles where women feel up to it.

Minority breast cancer patients tend to have higher rates of adjuvant treatment underuse. We implemented a web-based intervention that closes referral loops between surgeons and oncologists at inner-city safety net hospitals serving high volumes of minority breast cancer patients to assist these hospitals to improve care coordination.

Abstract and Introduction

Breast imaging has made huge advances in the last decade, and along with newer techniques to diagnose primary breast cancer, many novel methods are being used and look promising in detecting distant metastasis, recurrent disease and assessing response to treatment. Full-field digital mammography optimizes the lesion-background contrast and gives better sensitivity, and it is possible to see through the dense tissues by altering computer windows; this may be particularly useful in younger women with dense breasts. The need for repeat imaging is reduced, with the added advantage of reduced radiation dose to patients. Computer-aided detection systems may help the radiologist in interpretation of both conventional and digital mammograms. MRI has a role in screening women at high risk for breast cancer. It also aids in cancer management by assessing response to treatment and can help in deciding appropriate surgery by providing accurate information on the extent of the tumor. Newer diagnostic techniques such as sestamibi scans, optical imaging and molecular diagnostic techniques look promising, but need more investigation into their use. Their roles will appear clearer in coming years, and they may prove to be of help in further investigating lesions that are indeterminate on standard imaging. Other upcoming techniques are contrast-enhanced mammography and tomosynthesis. These may give additional information in indeterminate lesions, and when used in screening they aid in reducing recall rates, as shown in recent studies. PET/computed tomography has a role in detecting local disease recurrence and distant metastasis in breast cancer patients.

Prostate Problems Symptoms and Signs

  • The prostate is a gland that is a part of the male reproductive system that wraps around the male urethra near the bladder.
  • The gland is about the size of a walnut and grows larger as you age.
  • Enlargement of the prostate gland can cause symptoms, for example:
    1. Dribbling urine
    2. Pain or buring during urination
    3. Frequent urination
    4. Blood in the semen or urine
    5. Frequent pain or stiffness in the lower back, hips, pelvic or rectal area, or the upper thighs
    6. Urinary incontinence (the inability to urinate)
    7. Painful ejaculation
  • Common prostate problems in men include:
  • To diagnose the cause of the prostate problem, the doctor will do a rectal exam, patient history and take bacterial cultures if infection is suspected and ruling out prostate cancer.
  • Prostate cancer is common in men over 50, especially in African Americans and in men who eat fatty food and/or have a father or brother with prostate cancer.
  • Initiial procedures and tests to diagnose prostate cancer may include:
    • A rectal exam
    • Ultrasound
    • Assessment of prostate-specific antigen (PSA) levels
  • Prostate cancer is definitively diagnosed by a tissue biopsy.
  • Treatments for prostate cancer may include:
  • Many, but not all, doctors believe that men under the age of 75 should have yearly PSA tests.
  • Identifying prostate problems early is a way to reduce future prostate problems.